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DNA POLYMERASES WITH INCREASED 3

来源:华佗健康网
专利内容由知识产权出版社提供

专利名称:DNA POLYMERASES WITH INCREASED 3’-MISMATCH DISCRIMINATION

发明人:Fred Reichert,Keith Bauer,Thomas W. Myers申请号:US15868726申请日:20180111

公开号:US20180142221A1公开日:20180524

摘要:Disclosed are mutant DNA polymerases having increased 3′-mismatchdiscrimination relative to a corresponding, unmodified polymerase. The mutantpolymerases are useful in a variety of disclosed primer extension methods. Also

disclosed are related compositions, including recombinant nucleic acids, vectors, and hostcells, which are useful, e.g., for production of the mutant DNA polymerases.

申请人:Roche Molecular Systems, Inc.

地址:Pleasanton CA US

国籍:US

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