Poly(glycolic acid)poly(alkylene glycol)block cop

专利名称：Poly(glycolic acid)/poly(alkylene

glycol)block copolymers and method ofmanufacturing the same

发明人：Casey, Donald James,Huffman, Kenneth

Robert

申请号：EP831099申请日：19831005公开号：EP01012A3公开日：19851023

摘要：Multiblock copolymers having the following general formula: where Rrepresents alkylene and Ar is an aromatic group, are obtained by transesterification ofpoly(glycolic acid) and an hydroxyl-ended poly(alkylene glycol) such as poly(oxyethylene)in the presence of a catalyst with the degree of polymerization of the copolymer beingincreased by the subsequent addition of an aromatic orthocarbonate such as tetra-p-tolyl orthocarbonate. The copolymers find use in the manufacture of surgical articles,particularly absorbable monofilament sutures possessing the desired characteristics offlexibility, resulting in good handling properties, and biodegradability.

申请人：AMERICAN CYANAMID COMPANY

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