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PURIFICATION OF TPA FROM CRUDE PREPARATIONS

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专利名称:PURIFICATION OF TPA FROM CRUDE

PREPARATIONS

发明人:MITSUYOSHI MORII,MASAHARA

OHOKA,TOSHIHIKO SUZUKI,KATSUYUKISUZUKI,NOBUHIRO KAWASHIMA,NORIKOMORII,KUNIZOU MORI

申请号:AU7666687申请日:19870807公开号:AU586756B2公开日:190720

摘要:Tissue plasminogen activator (tPA) species having a specific molecular weightcan be isolated in a purified form from a crude tPA preparation containing various tPAspecies having different molecular weights by bringing the crude tPA preparation intocontact with hydroxyapatite and then separately eluting the adsorbed tPA species witheluents having different pHs and/or salt concentrations.

申请人:MITSUI TOATSU CHEMICALS, INCORPORATED

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