Method for the quantitative determination of prote

专利名称：Method for the quantitative determination

of protein-C and an activating preparationfor its implementation.

发明人：STOCKER, KURT F.,SVENDSEN, LARS G.申请号：EP86106881.5申请日：19860521公开号：EP0203509B1公开日：19910403

摘要：A method and composition for assaying protein C is described. The methodcomprises reacting a protein C-containing medium with a protein C-activating activatorpreparation obtained from venom of the snake Agkistrodon contortrix, or venom ofanother snake species which undergoes an immunological cross-reaction with the venomof Agkistrodon contortrix, to cause maximum activation of protein C and subsequentlydetermining the quantity of activated protein C, said quantity being proportional to theamount of protein C in said medium. Also disclosed is a method and composition fortreating thrombotic disorders with the activator preparation and a method of obtainingthe activator preparation by culturing of a cloned microorganism.

申请人：PENTAPHARM A.G.,PENTAPHARM A.G.

地址：ENGELGASSE 109; CH-4052 BASEL,ENGELGASSE 109; CH-4052 BASEL

代理机构：Braun, André, jr.

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