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世界卫生组织国际癌症研究机构一类致癌物清单

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世界卫生组织国际癌症研究机构致癌物清单

1类致癌物清单(共120种)

1类致癌物:对人为确定致癌物。序号1234567101112131415161718192021222324252627282930英文名称Acetaldehyde associated with consumption of alcoholicbeveragesAcheson process, occupational exposure associated withAcid mists, strong inorganicAflatoxinsAlcoholic beveragesAluminium production4-AminobiphenylAreca nutAristolochic acidAristolochic acid, plants containingArsenic and inorganic arsenic compoundsAsbestos (all forms, including actinolite, amosite,anthophyllite, chrysotile, crocidolite, tremolite)Auramine productionAzathioprineBenzeneBenzidineBenzidine, dyes metabolized toBenzo[ a ]pyreneBeryllium and beryllium compoundsBetel quid with tobaccoBetel quid without tobaccoBis(chloromethyl)ether; chloromethyl methyl ether(technical-grade)Busulfan1,3-ButadieneCadmium and cadmium compoundsChlorambucilChlornaphazineChromium (VI) compoundsClonorchis sinensis (infection with)Coal gasification中文名称与酒精饮料摄入有关的乙醛与职业暴露有关的艾其逊法(用电弧炉制碳化矽)强无机酸雾黄曲霉毒素含酒精饮料铝生产4-氨基联苯槟榔果马兜铃酸含马兜铃酸的植物砷和无机砷化合物石棉(各种形式,包括阳起石、铁石绵、直闪石、温石棉、青石棉、透闪石)金胺生产硫唑嘌呤苯联苯胺染料代谢产生的联苯胺苯并[a]芘铍和铍化合物含烟草的槟榔嚼块不含烟草的槟榔嚼块双(氯甲基)醚;氯甲基甲基醚(工业级)白消安1,3-丁二烯镉及镉化合物苯丁酸氮芥萘氮芥铬(6价)化合物华支睾吸虫(感染)煤炭气化时间(年)20122017201220122012201220122012201220122012201220122012In prep.2012201220122012201220122012201220122012201220122012201220123132333435363738394041424344474849505152535556575859606162636566Coal, indoor emissions from household combustion ofCoal-tar distillationCoal-tar pitchCoke productionCyclophosphamideCyclosporine1,2-DichloropropaneDiethylstilbestrolEngine exhaust, dieselEpstein-Barr virusErioniteEstrogen therapy, postmenopausalEstrogen-progestogen menopausal therapy (combined)Estrogen-progestogen oral contraceptives (combined)Ethanol in alcoholic beveragesEthylene oxideEtoposideEtoposide in combination with cisplatin and bleomycinFission products, including strontium-90Fluoro-edenite fibrous amphiboleFormaldehydeHaematite mining (underground)Helicobacter pylori(infection with)Hepatitis B virus (chronic infection with)Hepatitis C virus (chronic infection with)Human immunodeficiency virus type 1 (infection with)Human papillomavirus types 16, 18, 31, 33, 35, 39, 45,51, 52, 56, 58, 59Human T-cell lymphotropic virus type IIonizing radiation (all types)Iron and steel founding (occupational exposure during)Isopropyl alcohol manufacture using strong acidsKaposi sarcoma herpesvirusLeather dustLindane (see also Hexachlorocyclohexanes)Magenta productionMelphalan家庭烧煤室内排放煤焦油蒸馏煤焦油沥青焦炭生产环磷酰胺环孢菌素1,2-二氯丙烷己烯雌酚柴油发动机排气爱泼斯坦-巴尔病毒毛沸石绝经后雌激素治疗雌激素-孕激素更年期治疗(合用)雌激素-孕激素口服避孕药(合用)含酒精饮料中的乙醇环氧乙烷依托泊苷依托泊苷与顺铂和博来霉素合用裂变产物,包括锶- 90氟代-浅闪石纤维状角闪石甲醛赤铁矿开采(地下)幽门螺杆菌(感染)乙型肝炎病毒(慢性感染)丙型肝炎病毒(慢性感染)人免疫缺陷病毒I型(感染)人乳头瘤病毒16,18,31,33,35,39,45,51,52,56,58,59型人嗜T淋巴细胞病毒I型电离辐射(所有类型)钢铁铸造(职业暴露)使用强酸生产异丙醇卡波氏肉瘤疱疹病毒皮革粉末林丹(参见六氯环己烷)品红生产美法仑201220122012201220122012201720122014201220122012201220122012201220122012201220172012201220122012201220122012201220122012201220122012In prep.20122012676869707172737475767778798081828384858687809192939495969799100Methoxsalen (8-methoxypsoralen) plus ultraviolet Aradiation4,4'-Methylenebis(2-chloroaniline) (MOCA)Mineral oils, untreated or mildly treatedMOPP and other combined chemotherapy includingalkylating agents2-NaphthylamineNeutron radiationNickel compoundsN'-Nitrosonornicotine (NNN) and 4-(N-Nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK)Opisthorchis viverrini(infection with)Outdoor air pollutionOutdoor air pollution, particulate matter inPainter (occupational exposure as a)3,4,5,3’,4’-Pentachlorobiphenyl (PCB-126)2,3,4,7,8-PentachlorodibenzofuranPentachlorophenol (see also Polychlorophenols)PhenacetinPhenacetin, analgesic mixtures containingPhosphorus-32, as phosphatePlutoniumPolychlorinated biphenylsPolychlorinated biphenyls, dioxin-like, with a ToxicityEquivalency Factor (TEF) according to WHO (PCBs 77,81, 105, 114, 118, 123, 126, 156, 157, 167, 169, 1)Processed meat (consumption of)Radioiodines, including iodine-131Radionuclides, alpha-particle-emitting, internallydepositedRadionuclides, beta-particle-emitting, internallydepositedRadium-224 and its decay productsRadium-226 and its decay productsRadium-228 and its decay productsRadon-222 and its decay productsRubber manufacturing industrySalted fish, Chinese-styleSchistosoma haematobium (infection with)花椒毒素(8-甲氧基补骨脂素)伴紫外线A辐射4,4'-亚甲基二(2-氯苯胺)(MOCA)未经处理或轻度处理矿物油MOPP(氮芥、长春新碱、甲基苄肼、强的松)及其他含烷化剂的联合化疗2-萘胺中子辐射镍化合物N'-亚硝基降烟碱(NNN)和4-(N-甲基亚硝胺基)-1-(3-吡啶基)-麝后睾吸虫(感染)室外空气污染含颗粒物的室外空气污染画家,油漆工,粉刷工等(职业暴露)3,4,5,3',4'-五氯联苯(PCB-126)2,3,4,7,8-五氯二苯并呋喃五氯苯酚(参见聚氯苯酚)非那西汀含非那西汀的止痛剂混合物磷-32,磷酸盐形式钚多氯联苯类二恶英多氯联苯,具有WHO毒性当量因子(TEF)(多氯联苯 77, 81, 105,114, 118, 123, 126, 156, 157, 167, 169,1)加工过的肉类(摄入)放射性碘,包括碘-131放射性核素,α粒子放射,内部沉积放射性核素,β粒子放射,内部沉积镭- 224及其衰变产物镭- 226及其衰变产物镭- 228及其衰变产物氡- 222及其衰变产物橡胶制造业中式咸鱼埃及血吸虫(感染)20122012201220122012201220122012201220162016201220122012In prep.201220122012201220162016In prep.201220122012201220122012201220122012201220122012Semustine [1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-司莫司汀[1-(2-氯乙基)-3-(4-甲基环nitrosourea, Methyl-CCNU]己基)-1-亚硝基脲,甲基-环已亚硝脲]Shale oils页岩油101102103104105106107108109110111112113114115116117118119120Silica dust, crystalline, in the form of quartz orcristobaliteSolar radiationSoot (as found in occupational exposure of chimneysweeps)Sulfur mustardTamoxifen2,3,7,8-Tetrachlorodibenzo-para-dioxinThiotepaThorium-232 and its decay productsTobacco smoke, second-handTobacco smokingTobacco, smokelessortho-ToluidineTreosulfanTrichloroethyleneUltraviolet-emitting tanning devicesUltraviolet radiation (wavelengths 100-400 nm,encompassing UVA, UVB, and UVC)Vinyl chlorideWelding fumesWood dustX- and Gamma-Radiation石英或方石英形式的晶状硅尘太阳辐射煤烟(烟囱清洁工的职业暴露))硫芥子气他莫昔芬2,3,7,8-四氯二苯并对二恶英三胺硫磷钍-232及其衰变产物二手烟草烟雾吸烟无烟烟草邻-甲苯胺曲奥舒凡三氯乙烯紫外发光日光浴设备紫外线辐射(波长100-400 nm,包括UVA、UVB和UVC)氯乙烯焊接烟尘木尘X射线和伽马射线辐射201220122012201220122012201220122012201220122012201220142012In prep.2012In prep.20122012备注:In prep.表示相关研究结果尚未以电子版或印刷版形式公布。

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