专利名称：Human GM-CSF antigen binding proteins发明人：Kirchner, Jacqueline A,Brasel, Kenneth
A,Olson, Kara,Escobar, Jose Carlos,Barone,Dauphine
申请号：EP101672.0申请日：20080918公开号：EP2236519A1公开日：20101006
摘要：Antigen binding proteins that bind to human GM-CSF protein are provided.Nucleic acids encoding the antigen binding protein, vectors, and cells encoding the sameare also provided. The antigen binding proteins can inhibit binding of GM-CSF to GM-CSFR, inhibit GM-CSF-induced proliferation and signaling of myeloid lineage cell lines andinhibit GM-CSF-induced activation of human monocytes.
申请人：Amgen, Inc
地址：One Amgen Center Drive Thousand Oaks, CA 91320-1799 US
国籍：US
代理机构：Care, Alison
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