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Method for simultaneous production of multiple pro

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专利名称:Method for simultaneous production of

multiple proteins; vectors and cells for usetherein

发明人:Arie Pieter Otte,Arthur Leo

Kruckeberg,Richard George AntoniusBernardus Sewalt

申请号:US11013031申请日:20041214公开号:US073878B2公开日:20080429

摘要:The invention relates to the field of biochemistry, molecular biology,pharmacology and diagnosis. More specifically the present invention relates to theproduction of proteins in a host cell. Even more specifically, the invention relates to amethod for improving expression of two or more proteins in a (host) cell. The method issuited for production of, for example, recombinant antibodies that can be used in apharmaceutical preparation or as a diagnostic tool. In one embodiment, the inventionprovides a method for obtaining a cell which expresses two or more proteins comprisingproviding the cell with two or more protein expression units encoding two or moreproteins, characterized in that at least two of the protein expression units comprise atleast one STAR sequence.

申请人:Arie Pieter Otte,Arthur Leo Kruckeberg,Richard George Antonius BernardusSewalt

地址:Amersfoort NL,Shoreline WA US,Arnhem NL

国籍:NL,US,NL

代理机构:TraskBritt

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