Process for mammalian cell suspension cultivation

专利名称：Process for mammalian cell suspension

cultivation device therefor and use in theproduction of proteins

发明人：BOEDEKER, BERTHOLD, DR.,HEWLETT, GUY,

DR.,SCHLUMBERGER, HORST DIETER, PROF.DR.,BUENTEMEYER, HEINO,LEHMANN,JUERGEN, DR.

申请号：EP87117285.4申请日：19871124公开号：EP0270908A2公开日：19880615

摘要：The process entails the medium being exchanged by ultrafiltration. The culturemedium is first removed from the reactor through a microporous membrane to give acell-free medium. This medium is passed to an ultrafiltration membrane for

ultrafiltration. The filtrate containing low molecular weight components and metabolicproducts is discarded, and the concentrate is returned to the reactor. Fresh mediumcorresponding to the amount of filtrate is fed into the reactor from a medium reservoir.

申请人：BAYER AG

地址：51368 Leverkusen DE

国籍：DE

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