Method for specifically detecting, isolating and c

专利名称：Method for specifically detecting, isolating

and characterizing cells from body samplesby transfecting nucleic acid constructs

发明人：Ralph Wirtz申请号：US10474078申请日：20040319

公开号：US200402193A1公开日：20041104

摘要：A method for detecting or isolating disease-associated cells or pluripotentstem cells from body samples is provided where cells of a body sample are transfectedwith nucleic acid constructs that include the following components: (a) a promoterelement containing at least one DNA site for binding one or more transcription factors;and (b) a reporter gene that enables the diseased or stem cells to be detected. Whenthe method is used for detecting disease-associated cells, the transcription factorinitiates at least one signalling activity in the disease-associated cells that is not presentin healthy cells.

申请人：WIRTZ RALPH

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