Process and apparatus for the preparation of a con

专利名称：Process and apparatus for the preparation

of a controllable and reproduceabletemperature gradient, and its use

发明人：ROSENBAUM, VOLKER, DIPL.-PHYS.,RIESNER,

DETLEV, PROF.-DR.

申请号：EP87109432.2申请日：19870701公开号：EP0251306B1公开日：19921021

摘要：The temperature gradient in a predetermined direction of thermally conductiveplates (1) for the separation of mixtures of substances in sheet-type separation media isestablished by heating one edge (2) of a plate by means of one or more controllableheating devices (4) and cooling the opposite edge (3) of the plate by means of one ormore controllable cooling devices (5), the energy flux of the heating device(s) (4) on theone hand and that of the cooling device(s) (5) on the other hand being greater than theenergy flux through the plate (1). This process and this apparatus are suitable for theseparation of mixtures of substances in which at least one component undergoes athermal transformation in the temperature range of the temperature gradient. It istherefore suitable for detecting and distinguishing viroids, satellite RNAs, viruses withdouble-stranded or cyclic nucleic acid, and for the analysis of protein/nucleic acidcomplexes and of mutations. ……

申请人：DIAGEN INSTITUT FUER MOLEKULARBIOLOGISCHE DIAGNOSTIKGMBH,DIAGEN INSTITUT FUER MOLEKULARBIOLOGISCHE DIAGNOSTIK GMBH

地址：MAX-VOLMER-STR. 4; W-4010 HILDEN,MAX-VOLMER-STR. 4; W-4010 HILDEN

代理机构：Werner, Hans-Karsten, Dr.Dipl.-Chem.

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